jslock.cpp in Mozilla Firefox 3.x before 3.0.2, Firefox 2.x before 2.0.0.18, Thunderbird 2.x before 2.0.0.18, and SeaMonkey 1.x before 1.1.13 allows remote attackers to cause a denial of service (crash) and possibly execute arbitrary code by modifying the window.__proto__.__proto__ object in a way that causes a lock on a non-native object, which triggers an assertion failure related to the OBJ_IS_NATIVE function.
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